BDBM228255 3-methyl-8-(6-(1-methyl-1H-pyrazol-4-yl)pyridin-3-yl)-1-(1-(methanesulfonyl)piperidin-3-yl)-1H-imidazo[4,5-c][1,5]naphthyridin-2(3H)-one::US10047084, 37

SMILES Cn1cc(cn1)-c1ccc(cn1)-c1ccc2ncc3n(C)c(=O)n(C4CCCN(C4)S(C)(=O)=O)c3c2n1

InChI Key InChIKey=WHTSBMSQTGKAIG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 228255   

TargetSerine/threonine-protein kinase mTOR(Human)
Beijing Forelandpharma

US Patent
LigandPNGBDBM228255(US10047084, 37 | 3-methyl-8-(6-(1-methyl-1H-pyrazo...)
Affinity DataIC50: 10nMAssay Description:The inhibition of the mTOR protein kinase activity by the compounds was determined by the enzymatic activity assay in vitro. The detection kit suppli...More data for this Ligand-Target Pair
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Date in BDB:
10/10/2018
Entry Details
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