BDBM228212 1-(1-ethylpyrrolidin-3-yl)-3-methyl-8-(6-(1-methyl-1H-pyrazol-4-yl)pyridin-3-yl)-1H-imidazo[4,5-c]quinolin-2(3H)-one::US10047084, 10

SMILES CCN1CCC(C1)n1c2c(cnc3ccc(cc23)-c2ccc(nc2)-c2cnn(C)c2)n(C)c1=O

InChI Key InChIKey=MFSIQXZMMHNVJD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 228212   

TargetSerine/threonine-protein kinase mTOR(Human)
Beijing Forelandpharma

US Patent
LigandPNGBDBM228212(US10047084, 10 | 1-(1-ethylpyrrolidin-3-yl)-3-meth...)
Affinity DataIC50: 550nMAssay Description:The inhibition of the mTOR protein kinase activity by the compounds was determined by the enzymatic activity assay in vitro. The detection kit suppli...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2018
Entry Details
Go to US Patent