BDBM2281 3-(benzenesulfinyl)-2-[(benzenesulfinyl)methyl]-1H-indole::5Cl3PhS-2IndolCONH2 inhibitor 6a

SMILES O=S(Cc1[nH]c2ccccc2c1S(=O)c1ccccc1)c1ccccc1

InChI Key InChIKey=AMRCRTWECQWVMW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 2281   

TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandPNGBDBM2281(3-(benzenesulfinyl)-2-[(benzenesulfinyl)methyl]-1H...)
Affinity DataIC50: 7.28E+4nMpH: 8.2Assay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2004
Entry Details Article
PubMed