BDBM228078 US9556160, ex 118

SMILES NC(=N)CC(=O)OCc1cccc(N2CCN(CC2)c2cnc(nc2)N2CC[C@@H](F)C2)c1F

InChI Key InChIKey=GEDJEVWKEXGKGR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 228078   

TargetAmine oxidase [copper-containing] 3(Human)
Astellas Pharma

US Patent
LigandPNGBDBM228078(US9556160, ex 118)
Affinity DataIC50: 29nMT: 2°CAssay Description:A human VAP-1 enzyme (SSAO) (reference: J Exp Med. 1998 Jul. 6; 188(1): 17 to 27) activity was measured by a radiochemistry-enzymatic assay using 14C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2018
Entry Details
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TargetMembrane primary amine oxidase(Rat)
Astellas Pharma

US Patent
LigandPNGBDBM228078(US9556160, ex 118)
Affinity DataIC50: 1.70nMT: 2°CAssay Description:A rat VAP-1 enzyme (SSAO) (reference: Biol Pharm Bull. 2005 March; 28(3): 413-8) activity was measured by a radiochemistry-enzymatic assay using 14C-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2018
Entry Details
Go to US Patent