BDBM2280 2-[(benzenesulfinyl)methyl]-5-chloro-3-(phenylsulfanyl)-1H-indole::5Cl3PhS-2IndolCONH2 inhibitor 5b

SMILES Clc1ccc2[nH]c(CS(=O)c3ccccc3)c(Sc3ccccc3)c2c1

InChI Key InChIKey=JSXXSKIISLBDCU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 2280   

TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandPNGBDBM2280(2-[(benzenesulfinyl)methyl]-5-chloro-3-(phenylsulf...)
Affinity DataIC50: 112nMpH: 8.2Assay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2004
Entry Details Article
PubMed