BDBM227719 3-bromo-n-(6-methoxy-1h-indazol-5-yl)-1h-pyrazolo[3,4-d]pyrimidin-4-amine::US9556181, 10::US9556181, 16::US9556181, 4::US9556181, 7

SMILES COc1cc2[nH]ncc2cc1Nc1ncnc2[nH]nc(Br)c12

InChI Key InChIKey=LRDFKVBDTBLENH-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 227719   

TargetMAP kinase-interacting serine/threonine-protein kinase 1 [1-424](Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM227719(US9556181, 4 | US9556181, 16 | US9556181, 7 | 3-br...)
Affinity DataIC50: 3nMpH: 7.5Assay Description:TBDA recombinant fusion protein of Glutathione-S-Transferase (GST, N-terminally) and human full-length MKNK1 (amino acids 1-424 and T344D of accessio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2018
Entry Details
Go to US Patent

TargetMAP kinase-interacting serine/threonine-protein kinase 1 [1-424](Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM227719(US9556181, 4 | US9556181, 16 | US9556181, 7 | 3-br...)
Affinity DataIC50: 6nMpH: 7.5Assay Description:TBDA recombinant fusion protein of Glutathione-S-Transferase (GST, N-terminally) and human full-length MKNK1 (amino acids 1-424 and T344D of accessio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2018
Entry Details
Go to US Patent

TargetMAP kinase-interacting serine/threonine-protein kinase 1 [1-424](Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM227719(US9556181, 4 | US9556181, 16 | US9556181, 7 | 3-br...)
Affinity DataIC50: 2nMpH: 7.5Assay Description:TBDA recombinant fusion protein of Glutathione-S-Transferase (GST, N-terminally) and human full-length MKNK1 (amino acids 1-424 and T344D of accessio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2018
Entry Details
Go to US Patent

TargetMAP kinase-interacting serine/threonine-protein kinase 1 [1-424](Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM227719(US9556181, 4 | US9556181, 16 | US9556181, 7 | 3-br...)
Affinity DataIC50: 1nMpH: 7.5Assay Description:TBDA recombinant fusion protein of Glutathione-S-Transferase (GST, N-terminally) and human full-length MKNK1 (amino acids 1-424 and T344D of accessio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2018
Entry Details
Go to US Patent