BDBM227717 US9556181, 2::n-(6-methoxy-1h-indazol-5-yl)-h-pyrazolo[3,4-d]pyrimidin-4-amine

SMILES COc1cc2[nH]ncc2cc1Nc1ncnc2[nH]ncc12

InChI Key InChIKey=IEAQCCACIFAOFD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 227717   

TargetMAP kinase-interacting serine/threonine-protein kinase 1 [1-424](Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM227717(US9556181, 2 | n-(6-methoxy-1h-indazol-5-yl)-h-pyr...)
Affinity DataIC50: 49nMpH: 7.5Assay Description:TBDA recombinant fusion protein of Glutathione-S-Transferase (GST, N-terminally) and human full-length MKNK1 (amino acids 1-424 and T344D of accessio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2018
Entry Details
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