BDBM227633 MTH1 inhibitor, 120

SMILES C(Nc1ncnc2[nH]cnc12)c1ccc2OCOc2c1

InChI Key InChIKey=YRSAPERCOVONIV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 227633   

TargetOxidized purine nucleoside triphosphate hydrolase(Human)
Riken Center For Life Science Technologies

LigandPNGBDBM227633(MTH1 inhibitor, 120)
Affinity DataIC50: 2.00E+4nMpH: 7.5Assay Description:Enzymatic reaction was initiated by adding either 8-oxo-dGTP (13.2 μm; TriLink BioTechnologies) or 2-OH-dATP (8.3 μm; Jena Bioscience) to r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2017
Entry Details Article
PubMed
TargetOxidized purine nucleoside triphosphate hydrolase(Human)
Riken Center For Life Science Technologies

LigandPNGBDBM227633(MTH1 inhibitor, 120)
Affinity DataIC50: 2.80E+4nMpH: 7.5Assay Description:Enzymatic reaction was initiated by adding either 8-oxo-dGTP (13.2 μm; TriLink BioTechnologies) or 2-OH-dATP (8.3 μm; Jena Bioscience) to r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2017
Entry Details Article
PubMed