BDBM227624 (E)-5-chloro-N'-(4-fluorobenzylidene)-1H-indole-2-carbohydrazide (28)

SMILES Fc1ccc(\C=N\NC(=O)c2cc3cc(Cl)ccc3[nH]2)cc1

InChI Key InChIKey=BOYYAPVHEYMDRN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 227624   

TargetBeta-glucuronidase(Human)
Universiti Teknologi Mara

LigandPNGBDBM227624((E)-5-chloro-N'-(4-fluorobenzylidene)-1H-indol...)
Affinity DataIC50: 6.50E+3nMAssay Description:β-glucuronidase activity was determined in accordance to method used by Taha et al. [Taha et al., Bioorg. Med. Chem., 23:7394-7404] by measuring...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2017
Entry Details

TargetBeta-glucuronidase(Human)
Universiti Teknologi Mara

LigandPNGBDBM227624((E)-5-chloro-N'-(4-fluorobenzylidene)-1H-indol...)
Affinity DataIC50: 6.50E+3nMAssay Description:Inhibition of beta-glucuronidase (unknown origin) using p-nitrophenyl-beta-d-glucuronide as substrate after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed