BDBM227559 US9340534, 14

SMILES OC(Cc1cccc(OC(F)(F)F)c1)\C=C\[C@H]1CCS(=O)(=O)N1CCCc1ccc(s1)C(O)=O

InChI Key InChIKey=NRRCMCUOXRAUBC-UHFFFAOYSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 227559   

TargetProstaglandin E2 receptor EP2 subtype(Human)
Allergan

US Patent
LigandPNGBDBM227559(US9340534, 14)
Affinity DataEC50:  38nMAssay Description:EP4 receptors couple to Gs and mediate elevations in cAMP concentration, although they do participate in other pathways as well. There are some redun...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2017
Entry Details
Go to US Patent

TargetProstaglandin E2 receptor EP2 subtype(Human)
Allergan

US Patent
LigandPNGBDBM227559(US9340534, 14)
Affinity DataEC50:  96nMpH: 7.4 T: 2°CAssay Description:HEK-293 cells stably expressing the human or feline FP receptor, or EP1, EP2, or EP4 receptors were washed with TME buffer, scraped from the bottom o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2017
Entry Details
Go to US Patent

TargetProstaglandin E2 receptor EP4 subtype(Human)
Allergan

US Patent
LigandPNGBDBM227559(US9340534, 14)
Affinity DataEC50:  1nMAssay Description:EP4 receptors couple to Gs and mediate elevations in cAMP concentration, although they do participate in other pathways as well. There are some redun...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2017
Entry Details
Go to US Patent

TargetProstaglandin E2 receptor EP4 subtype(Human)
Allergan

US Patent
LigandPNGBDBM227559(US9340534, 14)
Affinity DataEC50:  53nMpH: 7.4 T: 2°CAssay Description:HEK-293 cells stably expressing the human or feline FP receptor, or EP1, EP2, or EP4 receptors were washed with TME buffer, scraped from the bottom o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2017
Entry Details
Go to US Patent