BDBM226174 6-chloro-2-((5-(4-methoxyphenylamino)-1,3,4-thiadiazol-2-yl)methylthio)-3-(4-methoxyphenyl)quinazolin-4(3H)-one (29)

SMILES COc1ccc(Nc2nnc(CSc3nc4ccc(Cl)cc4c(=O)n3-c3ccc(OC)cc3)s2)cc1

InChI Key InChIKey=BIKFRCVHYDNBOQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 226174   

TargetDihydrofolate reductase(Bovine)
Future University

LigandPNGBDBM226174(6-chloro-2-((5-(4-methoxyphenylamino)-1,3,4-thiadi...)
Affinity DataIC50: 4.40E+3nMpH: 7.4 T: 2°CAssay Description:The assay mixture contained 50 μM Tris-HCl buffer (pH 7.4), 50 μM NADPH, 10 μl DMSO or the same volume of DMSO solution containing the...More data for this Ligand-Target Pair
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Date in BDB:
5/14/2017
Entry Details