BDBM226172 (6,7-Dimethoxy)-2-((4-(4-methoxyphenyl)-5-mercapto-4H-1,2,4-triazol-3-yl)methylthio)-3-(4-methoxyphenyl)quinazolin-4(3H)-one (27)

SMILES COc1ccc(cc1)-n1c(S)nnc1CSc1nc2cc(OC)c(OC)cc2c(=O)n1-c1ccc(OC)cc1

InChI Key InChIKey=DRYTVVUGEGPNGA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 226172   

TargetDihydrofolate reductase(Bovine)
Future University

LigandPNGBDBM226172((6,7-Dimethoxy)-2-((4-(4-methoxyphenyl)-5-mercapto...)
Affinity DataIC50: 1.08E+4nMpH: 7.4 T: 2°CAssay Description:The assay mixture contained 50 μM Tris-HCl buffer (pH 7.4), 50 μM NADPH, 10 μl DMSO or the same volume of DMSO solution containing the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2017
Entry Details