BDBM226169 1-[2-(6,7-Dimethoxy)-3-(4-methoxy-phenyl)-4-oxo-3,4-dihydroquinazolin-2-yl-thio)acetyl)-4-(4-chloro)phenyl]thiosemicarbazide (22)

SMILES COc1ccc(cc1)-n1c(SCC(=O)NNC(=S)c2ccc(Cl)cc2)nc2cc(OC)c(OC)cc2c1=O

InChI Key InChIKey=WHEQWVNBVIRLQQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 226169   

TargetDihydrofolate reductase(Bovine)
Future University

LigandPNGBDBM226169(1-[2-(6,7-Dimethoxy)-3-(4-methoxy-phenyl)-4-oxo-3,...)
Affinity DataIC50: 5.60E+4nMpH: 7.4 T: 2°CAssay Description:The assay mixture contained 50 μM Tris-HCl buffer (pH 7.4), 50 μM NADPH, 10 μl DMSO or the same volume of DMSO solution containing the...More data for this Ligand-Target Pair
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Date in BDB:
5/14/2017
Entry Details