BDBM226165 N'-[4-Methoxybenzylidene-2-(6-chloro)-3-(4-methoxy-phenyl)-4-oxo-3,4-dihydroquinazolin-2-yl-thio]acetohydrazide (17)

SMILES COc1ccc(\C=N\NC(=O)CSc2nc3ccc(Cl)cc3c(=O)n2-c2ccc(OC)cc2)cc1

InChI Key InChIKey=IGKDDNFFWVYXJT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 226165   

TargetDihydrofolate reductase(Bovine)
Future University

LigandPNGBDBM226165(N'-[4-Methoxybenzylidene-2-(6-chloro)-3-(4-met...)
Affinity DataIC50: 10nMpH: 7.4 T: 2°CAssay Description:The assay mixture contained 50 μM Tris-HCl buffer (pH 7.4), 50 μM NADPH, 10 μl DMSO or the same volume of DMSO solution containing the...More data for this Ligand-Target Pair
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Date in BDB:
5/14/2017
Entry Details