BDBM226162 2-[6-Chloro-3-(4-methoxyphenyl)-4-oxo-3,4-dihydroquinazolin-2-yl-thio] acetohydrazide (14)

SMILES COc1ccc(cc1)-n1c(SCC(=O)NN)nc2ccc(Cl)cc2c1=O

InChI Key InChIKey=HAQFYGQTKNWCJW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 226162   

TargetDihydrofolate reductase(Bovine)
Future University

LigandPNGBDBM226162(2-[6-Chloro-3-(4-methoxyphenyl)-4-oxo-3,4-dihydroq...)
Affinity DataIC50: 7.50E+3nMpH: 7.4 T: 2°CAssay Description:The assay mixture contained 50 μM Tris-HCl buffer (pH 7.4), 50 μM NADPH, 10 μl DMSO or the same volume of DMSO solution containing the...More data for this Ligand-Target Pair
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Date in BDB:
5/14/2017
Entry Details