BDBM226161 Ethyl 2-(6,7-dimethoxy-3-(4-methoxyphenyl)-4-oxo-3,4-dihydroquinazolin-2-yl-thio)acetate (13)

SMILES CCOC(=O)CSc1nc2cc(OC)c(OC)cc2c(=O)n1-c1ccc(OC)cc1

InChI Key InChIKey=HOWNJJPOSZGTCO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 226161   

TargetDihydrofolate reductase(Bovine)
Future University

LigandPNGBDBM226161(Ethyl 2-(6,7-dimethoxy-3-(4-methoxyphenyl)-4-oxo-3...)
Affinity DataIC50: 1.44E+4nMpH: 7.4 T: 2°CAssay Description:The assay mixture contained 50 μM Tris-HCl buffer (pH 7.4), 50 μM NADPH, 10 μl DMSO or the same volume of DMSO solution containing the...More data for this Ligand-Target Pair
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Date in BDB:
5/14/2017
Entry Details