BDBM226159 (6,7-Dimethoxy)-2-mercapto-3-(4-methoxyphenyl)quinazolin-4(3H)-ones (11)

SMILES COc1ccc(cc1)-n1c(=S)[nH]c2cc(OC)c(OC)cc2c1=O

InChI Key InChIKey=VQNWOOQBZPWILF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 226159   

TargetDihydrofolate reductase(Bovine)
Future University

LigandPNGBDBM226159((6,7-Dimethoxy)-2-mercapto-3-(4-methoxyphenyl)quin...)
Affinity DataIC50: 2.90E+4nMpH: 7.4 T: 2°CAssay Description:The assay mixture contained 50 μM Tris-HCl buffer (pH 7.4), 50 μM NADPH, 10 μl DMSO or the same volume of DMSO solution containing the...More data for this Ligand-Target Pair
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Date in BDB:
5/14/2017
Entry Details