BDBM226157 PTP1B spring 7 (7)

SMILES COc1ccc(-c2ccc(O)cc2)c(C(c2ccc(O)cc2)c2ccc(O)cc2)c1C#Cc1ccc(O)cc1

InChI Key InChIKey=QQJAYBCWBNSBME-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 226157   

TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Catholic University of Daegu

LigandPNGBDBM226157(PTP1B spring 7 (7))
Affinity DataKi:  3.00E+3nM ΔG°:  -7.83kcal/mole IC50: 4.80E+3nMpH: 6.0 T: 2°CAssay Description:In each 96-well plates (total 200 μL of volume), there were 2 mM p-NPP and PTP1B (0.05-0.1 μg) in a buffer containing 50 mM citrate (pH 6.0...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2017
Entry Details