BDBM226139 1-(4-Chloro-benzyl)-2-methyl-2-propyl-2,3-dihydro-1H-quinazolin-4-one (2t)

SMILES CCCC1(C)NC(=O)c2ccccc2N1Cc1ccc(Cl)cc1

InChI Key InChIKey=RKBFTMFAPRVJJR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 226139   

TargetAcetylcholinesterase(Electric eel)
University of Sargodha

LigandPNGBDBM226139(1-(4-Chloro-benzyl)-2-methyl-2-propyl-2,3-dihydro-...)
Affinity DataIC50: 2.40E+3nMpH: 8.0 T: 2°CAssay Description:AChE and BChE inhibitory assay was carried out by following Ellman's methodology [Ellman et al., Biochem. Pharmacol., 7:88-95] using AChE (Electric e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2017
Entry Details

TargetCarboxylic ester hydrolase(Horse)
University of Sargodha

LigandPNGBDBM226139(1-(4-Chloro-benzyl)-2-methyl-2-propyl-2,3-dihydro-...)
Affinity DataIC50: 4.60E+3nMpH: 8.0 T: 2°CAssay Description:AChE and BChE inhibitory assay was carried out by following Ellman's methodology [Ellman et al., Biochem. Pharmacol., 7:88-95] using AChE (Electric e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2017
Entry Details