BDBM22552 (4R)-4-benzyl-2-[3-(1H-imidazol-4-ylmethyl)phenyl]-4,5-dihydro-1,3-oxazole::4-Benzyl-1H-imidazole derivative, 30

SMILES C([C@@H]1COC(=N1)c1cccc(Cc2cnc[nH]2)c1)c1ccccc1

InChI Key InChIKey=CMXALEKLGZDBSD-UHFFFAOYSA-N

Data  1 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 22552   

TargetHistamine H3 receptor(Human)
Vu University Amsterdam

LigandPNGBDBM22552((4R)-4-benzyl-2-[3-(1H-imidazol-4-ylmethyl)phenyl]...)
Affinity DataKi:  89nM ΔG°:  -9.61kcal/mole EC50:  79nMpH: 7.4 T: 2°CAssay Description:Ligand displacement assays were performed on CHO cells membranes expressing hH3R. Retained radioactivity was determined by liquid scintillation count...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2008
Entry Details Article
PubMed