BDBM225274 2-[4-(4-Ethylpiperazin-1-yl)phenyl]-1H-benzo[d]imidazole (3b)

SMILES CCN1CCN(CC1)c1ccc(cc1)-c1nc2ccccc2[nH]1

InChI Key InChIKey=MJPUSTKHUHNRCG-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 225274   

TargetCarboxylic ester hydrolase(Horse)
Hacettepe University

LigandPNGBDBM225274(2-[4-(4-Ethylpiperazin-1-yl)phenyl]-1H-benzo[d]imi...)
Affinity DataIC50: 5.18E+3nMpH: 8.0 T: 2°CAssay Description:Reactions were performed in a mediumcontaining substrate (0.05-0.4 mM) combined with 0.125 mM DTNB in 100 mM 3-(N-morpholino)propanesulfonic acid buf...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2017
Entry Details

TargetAcetylcholinesterase(Human)
Hacettepe University

LigandPNGBDBM225274(2-[4-(4-Ethylpiperazin-1-yl)phenyl]-1H-benzo[d]imi...)
Affinity DataIC50: 3.49E+4nMpH: 8.0 T: 2°CAssay Description:Reactions were performed in a mediumcontaining substrate (0.05-0.4 mM) combined with 0.125 mM DTNB in 100 mM 3-(N-morpholino)propanesulfonic acid buf...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2017
Entry Details

TargetAcetylcholinesterase(Human)
Hacettepe University

LigandPNGBDBM225274(2-[4-(4-Ethylpiperazin-1-yl)phenyl]-1H-benzo[d]imi...)
Affinity DataIC50: 5.18E+3nMAssay Description:Inhibition of recombinant human AChE using acetylthiocholine iodide as substrate by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetCholinesterase(Horse)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM225274(2-[4-(4-Ethylpiperazin-1-yl)phenyl]-1H-benzo[d]imi...)
Affinity DataIC50: 3.49E+4nMAssay Description:Inhibition of equine serum BuChE using butyrylthiocholine iodide as substrate by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed