BDBM224808 US9328124, 8

SMILES CC(C)(O)c4nc(N3C[C@H]1CSC(N)=N[C@@]1(c2cnccn2)C3)ncc4F

InChI Key InChIKey=IKIJFJKFIYFTBZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 224808   

TargetBeta-secretase 1 [1-460](Human)
Eli Lilly

US Patent
LigandPNGBDBM224808(US9328124, 8)
Affinity DataIC50: 105nMpH: 4.6 T: 2°CAssay Description:Ten μL of each dilution is added to each well on row A to H of a corresponding low protein binding black plate containing the reaction mixture (25...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2017
Entry Details
Go to US Patent