BDBM224788 US9328120, 18 (enantiomer 1)

SMILES Cc1nnc(s1)[C@H]1CC[C@@H]1c1nc2n(ncc2c(=O)[nH]1)C1CCC(F)(F)CC1

InChI Key InChIKey=ZFKMGSPKDCVGEG-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 224788   

TargetIsoform PDE9A2 of High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A (PDE9A2)(Human)
Boehringer Ingelheim International

US Patent

LigandBDBM224788(US9328120, 18 (enantiomer 1))Copy SMILESCopy InChI

Affinity DataIC50: 5nMT: 2°CAssay Description:The PDE9A2 enzymatic activity assay was run as scintillation proximity assay (SPA), in general according to the protocol of the manufacturer (GE Heal...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
5/8/2017
Entry Details
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