BDBM224642 US9328111, 15

SMILES CC(C)(NC(=O)OCc1ccccc1)C(=O)N1CCc2c(C1)[nH]c1cccc3c1c2n[nH]c3=O

InChI Key InChIKey=IABJUUXTFVPVLU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 224642   

TargetPoly [ADP-ribose] polymerase 1(Human)
Beigene

US Patent
LigandPNGBDBM224642(US9328111, 15)
Affinity DataIC50: 23nMpH: 8.0Assay Description:PARP1 enzymatic assay was conducted using a method modified from HT F Homogeneous PARP Inhibition Assay Kit (Trevigen). 8.8 nM PARP1 was pre-incubate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2017
Entry Details
Go to US Patent