BDBM224620 US9326978, 33::US9326978, 49

SMILES Clc1ccc(Nc2nc3ccccc3c3[nH]c(nc23)C2CCCC2)cc1Cl

InChI Key InChIKey=SYNRBWNXNMPXNT-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 224620   

TargetAdenosine receptor A3(Human)
The United States of America, Represented By The Secretary, Dept. of Health and Human Services

US Patent
LigandPNGBDBM224620(US9326978, 49 | US9326978, 33)
Affinity DataKi:  4.69E+3nMpH: 8.0Assay Description:Each tube in the competitive binding assay contained 100 μl membrane suspension (20 μg protein), 50 μl [125I]-AB-MECA (0.5 nM), and 50...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2017
Entry Details
Go to US Patent

TargetAdenosine receptor A3(Human)
The United States of America, Represented By The Secretary, Dept. of Health and Human Services

US Patent
LigandPNGBDBM224620(US9326978, 49 | US9326978, 33)
Affinity DataKi:  4.69E+3nMpH: 8.0Assay Description:Each tube in the competitive binding assay contained 100 μl membrane suspension (20 μg protein), 50 μl [125I]-AB-MECA (0.5 nM), and 50...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2017
Entry Details
Go to US Patent

TargetAdenosine receptor A1(Human)
The United States of America, Represented By The Secretary, Dept. of Health and Human Services

US Patent
LigandPNGBDBM224620(US9326978, 49 | US9326978, 33)
Affinity DataKi: >1.00E+4nMpH: 7.4Assay Description:For binding to the human A1AR, [3H]R-PIA (2 nM) was incubated with membranes (40 μg/tube) from CHO cells stably expressing the human A1AR at 25°...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2017
Entry Details
Go to US Patent

TargetAdenosine receptor A2a(Human)
The United States of America, Represented By The Secretary, Dept. of Health and Human Services

US Patent
LigandPNGBDBM224620(US9326978, 49 | US9326978, 33)
Affinity DataKi: >1.00E+4nMpH: 7.4Assay Description:For binding to the human A1AR, [3H]R-PIA (2 nM) was incubated with membranes (40 μg/tube) from CHO cells stably expressing the human A1AR at 25°...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2017
Entry Details
Go to US Patent