BDBM224572 US9321773, 89

SMILES Nc1ncnc2n(Cc3nc4cccc(C#CCCCC(=O)N5CCCC5)c4c(=O)n3Cc3ccccc3Cl)nc(-c3ccc(O)cc3)c12

InChI Key InChIKey=GFPPJADRSAPASM-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 224572   

LigandPNGBDBM224572(US9321773, 89)
Affinity DataIC50: 3nMAssay Description:PI3 kinases catalyse the phosphorylation of phosphatidylinositol 4,5-biphosphate (PIP2) to phosphatidylinositol 3,4,5-triphosphate (PIP3) in the pres...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2017
Entry Details
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LigandPNGBDBM224572(US9321773, 89)
Affinity DataIC50: 47nMAssay Description:PI3 kinases catalyse the phosphorylation of phosphatidylinositol 4,5-biphosphate (PIP2) to phosphatidylinositol 3,4,5-triphosphate (PIP3) in the pres...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2017
Entry Details
Go to US Patent

LigandPNGBDBM224572(US9321773, 89)
Affinity DataIC50: 1.49E+3nMAssay Description:PI3 kinases catalyse the phosphorylation of phosphatidylinositol 4,5-biphosphate (PIP2) to phosphatidylinositol 3,4,5-triphosphate (PIP3) in the pres...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2017
Entry Details
Go to US Patent