BDBM224570 US9321773, 37

SMILES COCC#Cc1cccc2nc(Cn3nc(-c4cccc(O)c4)c4c(N)ncnc34)n(Cc3cccc(c3)C(F)(F)F)c(=O)c12

InChI Key InChIKey=WZVLLCCQFGLPMC-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 224570   

LigandPNGBDBM224570(US9321773, 37)
Affinity DataIC50: 12nMAssay Description:PI3 kinases catalyse the phosphorylation of phosphatidylinositol 4,5-biphosphate (PIP2) to phosphatidylinositol 3,4,5-triphosphate (PIP3) in the pres...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2017
Entry Details
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LigandPNGBDBM224570(US9321773, 37)
Affinity DataIC50: 1.61E+3nMAssay Description:PI3 kinases catalyse the phosphorylation of phosphatidylinositol 4,5-biphosphate (PIP2) to phosphatidylinositol 3,4,5-triphosphate (PIP3) in the pres...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2017
Entry Details
Go to US Patent

LigandPNGBDBM224570(US9321773, 37)
Affinity DataIC50: 474nMAssay Description:PI3 kinases catalyse the phosphorylation of phosphatidylinositol 4,5-biphosphate (PIP2) to phosphatidylinositol 3,4,5-triphosphate (PIP3) in the pres...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2017
Entry Details
Go to US Patent