BDBM224568 US9321773, 4

SMILES Nc1ncnc2n(Cc3nc4cccc(C#CCCCC(O)=O)c4c(=O)n3Cc3ccccc3Cl)nc(-c3ccc(O)cc3)c12

InChI Key InChIKey=NLAFCFUVNPEKMI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 224568   

LigandPNGBDBM224568(US9321773, 4)
Affinity DataIC50: 12nMAssay Description:PI3 kinases catalyse the phosphorylation of phosphatidylinositol 4,5-biphosphate (PIP2) to phosphatidylinositol 3,4,5-triphosphate (PIP3) in the pres...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2017
Entry Details
Go to US Patent

LigandPNGBDBM224568(US9321773, 4)
Affinity DataIC50: 20nMAssay Description:PI3 kinases catalyse the phosphorylation of phosphatidylinositol 4,5-biphosphate (PIP2) to phosphatidylinositol 3,4,5-triphosphate (PIP3) in the pres...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2017
Entry Details
Go to US Patent

LigandPNGBDBM224568(US9321773, 4)
Affinity DataIC50: 17nMAssay Description:PI3 kinases catalyse the phosphorylation of phosphatidylinositol 4,5-biphosphate (PIP2) to phosphatidylinositol 3,4,5-triphosphate (PIP3) in the pres...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2017
Entry Details
Go to US Patent