BDBM223925 US9328112, 147

SMILES CN1Cc2c([nH]c3nccc(-c4cc(F)c(F)cc14)c23)C1=CCN(CC(=O)N2CCC[C@H]2CO)CC1

InChI Key InChIKey=QFJRVRBVNPFQTL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 223925   

TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Abbvie

US Patent
LigandPNGBDBM223925(US9328112, 147)
Affinity DataIC50: 45nMAssay Description:CDK9 enzyme activities were measured using LANCE ULight TR-FRET kinase assay reagents (PerkinElmer, Waltham, Mass.). Compounds were diluted in 100% D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2017
Entry Details
Go to US Patent