BDBM223586 US9321766, 3

SMILES Cc1cc[nH]c(=O)c1N1CCc2nc(N)ncc2C1

InChI Key InChIKey=TZWRZQDQESUGPZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 223586   

TargetVascular endothelial growth factor receptor 2(Human)
Allergan

US Patent
LigandPNGBDBM223586(US9321766, 3)
Affinity DataIC50: 1.00E+4nMpH: 7.4 T: 2°CAssay Description:Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg/well of poly-Glu-Tyr (4:1) in 10 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2017
Entry Details
Go to US Patent

TargetPlatelet-derived growth factor receptor beta(Human)
Allergan

US Patent
LigandPNGBDBM223586(US9321766, 3)
Affinity DataIC50: 3.89E+3nMpH: 7.4 T: 2°CAssay Description:Biochemical PDGFR3 kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg of poly-Glu-Tyr (4:1) in 10 mM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2017
Entry Details
Go to US Patent