BDBM22349 1,3-Diarylprop-2-yn-1-one, 13f::3-(4-methanesulfonylphenyl)-1-[4-(trifluoromethyl)phenyl]prop-2-yn-1-one::CHEMBL194273

SMILES CS(=O)(=O)c1ccc(cc1)C#CC(=O)c1ccc(cc1)C(F)(F)F

InChI Key InChIKey=GJFAJGZOLWWKBV-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 22349   

TargetProstaglandin G/H synthase 1(Sheep)
University of Alberta

LigandPNGBDBM22349(3-(4-methanesulfonylphenyl)-1-[4-(trifluoromethyl)...)
Affinity DataIC50: 3.10E+3nMpH: 8.0 T: 2°CAssay Description:The COX enzyme activities were measured using the COX Inhibitor Screening Assay kit provided by Cayman (Cayman, Chemical Co., Ann Arbor, MI). The as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2008
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
University of Alberta

LigandPNGBDBM22349(3-(4-methanesulfonylphenyl)-1-[4-(trifluoromethyl)...)
Affinity DataIC50: 1.00E+5nMAssay Description:The COX enzyme activities were measured using the COX Inhibitor Screening Assay kit provided by Cayman (Cayman, Chemical Co., Ann Arbor, MI). The as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2008
Entry Details Article
PubMed
TargetLipoxygenase(Potato)
University of Alberta

LigandPNGBDBM22349(3-(4-methanesulfonylphenyl)-1-[4-(trifluoromethyl)...)
Affinity DataIC50: 1.00E+4nMAssay Description:The COX enzyme activities were measured using the COX Inhibitor Screening Assay kit provided by Cayman (Cayman, Chemical Co., Ann Arbor, MI). The as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2008
Entry Details Article
PubMed
TargetSeed linoleate 13S-lipoxygenase-1(Soybean)
University of Alberta

LigandPNGBDBM22349(3-(4-methanesulfonylphenyl)-1-[4-(trifluoromethyl)...)
Affinity DataIC50: 1.00E+4nMAssay Description:The COX enzyme activities were measured using the COX Inhibitor Screening Assay kit provided by Cayman (Cayman, Chemical Co., Ann Arbor, MI). The as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2008
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
University of Alberta

LigandPNGBDBM22349(3-(4-methanesulfonylphenyl)-1-[4-(trifluoromethyl)...)
Affinity DataIC50: 3.10E+3nMAssay Description:In vitro inhibitory activity against ovine cyclooxygenase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Sheep)
University of Alberta

Curated by ChEMBL
LigandPNGBDBM22349(3-(4-methanesulfonylphenyl)-1-[4-(trifluoromethyl)...)
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro inhibitory activity against ovine cyclooxygenase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetSeed linoleate 13S-lipoxygenase-1(Soybean)
University of Alberta

LigandPNGBDBM22349(3-(4-methanesulfonylphenyl)-1-[4-(trifluoromethyl)...)
Affinity DataIC50: 1.00E+4nMAssay Description:In vitro inhibitory activity against 5-lipoxygenase obtained from potatoMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetSeed linoleate 13S-lipoxygenase-1(Soybean)
University of Alberta

LigandPNGBDBM22349(3-(4-methanesulfonylphenyl)-1-[4-(trifluoromethyl)...)
Affinity DataIC50: 1.00E+4nMAssay Description:In vitro inhibitory activity against 15-lipoxygenase obtained from soybeanMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed