BDBM223480 US9320734, PtdIns(3,4,5)trisphosphate

SMILES CCCCCCCCCCCCCCCC(=O)OCC(COP([O-])(=O)OC1[C@H](O)[C@H](OP([O-])([O-])=O)C(OP([O-])([O-])=O)[C@H](OP([O-])([O-])=O)[C@H]1O)OC(=O)CCCCCCCCCCCCCCC

InChI Key InChIKey=ZSZXYWFCIKKZBT-UHFFFAOYSA-G

Data  1 KI  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 223480   

TargetRAC-alpha serine/threonine-protein kinase [1-123](Human)
The University of Texas System

US Patent
LigandPNGBDBM223480(US9320734, PtdIns(3,4,5)trisphosphate)
Affinity DataKd:  3.08E+3nMAssay Description:KT1 PH domain small molecule inhibitors were identified using the crystal structure of the AKT1 PH domain bound by PtdIns(1,3,4,5)P4 as descried in T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2017
Entry Details
Go to US Patent

TargetRAC-alpha serine/threonine-protein kinase [1-123](Human)
The University of Texas System

US Patent
LigandPNGBDBM223480(US9320734, PtdIns(3,4,5)trisphosphate)
Affinity DataKi:  260nMAssay Description:SPR interaction analyses were performed with a Biacore 2000, using Biacore 2000 Control Software v3.2 and BIAevaluation v4.1 analysis software (Biaco...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2017
Entry Details
Go to US Patent