BDBM223474 US9320734, 415

SMILES COc1cc(NS(=O)(=O)c2ccc(NS(=O)(=O)c3c(C)noc3C)cc2)nc(OC)n1

InChI Key InChIKey=SSDWSTAYENJABB-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 223474   

TargetRAC-alpha serine/threonine-protein kinase [1-123](Human)
The University of Texas System

US Patent
LigandPNGBDBM223474(US9320734, 415)
Affinity DataKd:  6.27E+3nMAssay Description:SPR interaction analyses were performed with a Biacore 2000, using Biacore 2000 Control Software v3.2 and BIAevaluation v4.1 analysis software (Biaco...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2017
Entry Details
Go to US Patent

TargetRAC-alpha serine/threonine-protein kinase [1-123](Human)
The University of Texas System

US Patent
LigandPNGBDBM223474(US9320734, 415)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of AKT was measured by Western blots using specific antibodies against phospho-Ser473-AKT in HT-29 lung cancer cells. Inhibition of the ph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2017
Entry Details
Go to US Patent