BDBM22345 1,3-Diarylprop-2-yn-1-one, 13b::3-(4-methanesulfonylphenyl)-1-(4-methylphenyl)prop-2-yn-1-one::CHEMBL194897

SMILES Cc1ccc(cc1)C(=O)C#Cc1ccc(cc1)S(C)(=O)=O

InChI Key InChIKey=MVEXLQMDJOVCFZ-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 22345   

TargetProstaglandin G/H synthase 1(Sheep)
University of Alberta

LigandPNGBDBM22345(CHEMBL194897 | 3-(4-methanesulfonylphenyl)-1-(4-me...)
Affinity DataIC50: 1.00E+5nMpH: 8.0 T: 2°CAssay Description:The COX enzyme activities were measured using the COX Inhibitor Screening Assay kit provided by Cayman (Cayman, Chemical Co., Ann Arbor, MI). The as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2008
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
University of Alberta

LigandPNGBDBM22345(CHEMBL194897 | 3-(4-methanesulfonylphenyl)-1-(4-me...)
Affinity DataIC50: 3.30E+4nMAssay Description:The COX enzyme activities were measured using the COX Inhibitor Screening Assay kit provided by Cayman (Cayman, Chemical Co., Ann Arbor, MI). The as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2008
Entry Details Article
PubMed
TargetLipoxygenase(Potato)
University of Alberta

LigandPNGBDBM22345(CHEMBL194897 | 3-(4-methanesulfonylphenyl)-1-(4-me...)
Affinity DataIC50: 1.00E+4nMAssay Description:The COX enzyme activities were measured using the COX Inhibitor Screening Assay kit provided by Cayman (Cayman, Chemical Co., Ann Arbor, MI). The as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2008
Entry Details Article
PubMed
TargetSeed linoleate 13S-lipoxygenase-1(Soybean)
University of Alberta

LigandPNGBDBM22345(CHEMBL194897 | 3-(4-methanesulfonylphenyl)-1-(4-me...)
Affinity DataIC50: 1.00E+4nMAssay Description:The COX enzyme activities were measured using the COX Inhibitor Screening Assay kit provided by Cayman (Cayman, Chemical Co., Ann Arbor, MI). The as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2008
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
University of Alberta

LigandPNGBDBM22345(CHEMBL194897 | 3-(4-methanesulfonylphenyl)-1-(4-me...)
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro inhibitory activity against ovine cyclooxygenase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetSeed linoleate 13S-lipoxygenase-1(Soybean)
University of Alberta

LigandPNGBDBM22345(CHEMBL194897 | 3-(4-methanesulfonylphenyl)-1-(4-me...)
Affinity DataIC50: 1.00E+4nMAssay Description:In vitro inhibitory activity against 5-lipoxygenase obtained from potatoMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetSeed linoleate 13S-lipoxygenase-1(Soybean)
University of Alberta

LigandPNGBDBM22345(CHEMBL194897 | 3-(4-methanesulfonylphenyl)-1-(4-me...)
Affinity DataIC50: 1.00E+4nMAssay Description:In vitro inhibitory activity against 15-lipoxygenase obtained from soybeanMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Sheep)
University of Alberta

Curated by ChEMBL
LigandPNGBDBM22345(CHEMBL194897 | 3-(4-methanesulfonylphenyl)-1-(4-me...)
Affinity DataIC50: 3.30E+4nMAssay Description:In vitro inhibitory activity against ovine cyclooxygenase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed