BDBM22330 2-amino-5-hydroxyindole, 11::5-hydroxy-2-[(1-phenylethyl)amino]-1H-indole-3-carbonitrile

SMILES CC(Nc1[nH]c2ccc(O)cc2c1C#N)c1ccccc1

InChI Key InChIKey=YUUDORNXNYABGN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 22330   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Friedrich Alexander University Erlangen

LigandPNGBDBM22330(5-hydroxy-2-[(1-phenylethyl)amino]-1H-indole-3-car...)
Affinity DataIC50: 1.00E+4nMpH: 7.4 T: 2°CAssay Description:Purified 5-LO was added to reaction mix containing the test compounds. For efficient inhibition of 5-LO, low hydroperoxide levels are important. Glut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2008
Entry Details Article
PubMed