BDBM223124 (Z)-N'-(5-bromo-1-(2-chlorobenzyl)-2-oxoindolin-3-ylidene)-2-((2-oxo-2H-chromen-7-yl)oxy)acetohydrazide (5s)

SMILES Clc1ccccc1CN1C(=O)\C(=N/NC(=O)COc2ccc3ccc(=O)oc3c2)c2cc(Br)ccc12

InChI Key InChIKey=STSXAQOGSQHOIE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 223124   

TargetAlpha-glucosidase MAL32(Baker's yeast)
Jishou University

LigandPNGBDBM223124((Z)-N'-(5-bromo-1-(2-chlorobenzyl)-2-oxoindoli...)
Affinity DataIC50: 2.85E+3nMpH: 6.8Assay Description:The test compounds were dissolved in DMSO to prepare the required distributing concentration. α-Glucosidase inhibitory activity was assayed usin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2017
Entry Details Article
PubMed
TargetProbable maltase-glucoamylase 2(Human)
Babasaheb Bhimrao Ambedkar University (A Central University)

Curated by ChEMBL
LigandPNGBDBM223124((Z)-N'-(5-bromo-1-(2-chlorobenzyl)-2-oxoindoli...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of alpha-glucosidase (unknown origin) using p-nitrophenyl-alpha-d-glucopyranoside as substrate preincubated for 15 mins followed by substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed