BDBM223080 (E)-N'-(1-(3-(4-fluorophenyl)-5-phenyl-4,5-dihydro-1H-pyrazol-1yl)ethylidene)isonicotino hydrazide (3j)

SMILES C\C(=N/NC(=O)c1ccncc1)N1N=C(CC1c1ccccc1)c1ccc(F)cc1

InChI Key InChIKey=IBRAYHGZVRBRCQ-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 223080   

Target5'-nucleotidase(Human)
Quaid-I-Azam University

LigandPNGBDBM223080((E)-N'-(1-(3-(4-fluorophenyl)-5-phenyl-4,5-dih...)
Affinity DataIC50: 190nMpH: 7.4 T: 2°CAssay Description:The enzymatic assay of both human and rat ecto-5'-nucleotidase were performed with slight modifications in the previously described method. The stock...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2017
Entry Details Article
PubMed
Target5'-nucleotidase(Rat)
Quaid-I-Azam University

LigandPNGBDBM223080((E)-N'-(1-(3-(4-fluorophenyl)-5-phenyl-4,5-dih...)
Affinity DataIC50: 360nMpH: 7.4 T: 2°CAssay Description:The enzymatic assay of both human and rat ecto-5'-nucleotidase were performed with slight modifications in the previously described method. The stock...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2017
Entry Details Article
PubMed
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Bovine)
Quaid-I-Azam University

LigandPNGBDBM223080((E)-N'-(1-(3-(4-fluorophenyl)-5-phenyl-4,5-dih...)
Affinity DataIC50: 1.06E+3nMpH: 9.8 T: 2°CAssay Description:The assay conditions were optimized with some changes in formerly reported spectrophotometric method. The composition of assay buffer of pH 9.8 was a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2017
Entry Details Article
PubMed
TargetIntestinal-type alkaline phosphatase(Bovine)
Quaid-I-Azam University

LigandPNGBDBM223080((E)-N'-(1-(3-(4-fluorophenyl)-5-phenyl-4,5-dih...)
Affinity DataIC50: 3.98E+3nMpH: 9.8 T: 2°CAssay Description:The assay conditions were optimized with some changes in formerly reported spectrophotometric method. The composition of assay buffer of pH 9.8 was a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2017
Entry Details Article
PubMed
Target5'-nucleotidase(Human)
Quaid-I-Azam University

LigandPNGBDBM223080((E)-N'-(1-(3-(4-fluorophenyl)-5-phenyl-4,5-dih...)
Affinity DataIC50: 190nMAssay Description:Inhibition of human N-terminal Ecto-5'-nucleotidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
Target5'-nucleotidase(Mouse)
Federal University of Rio Grande Do Sul

Curated by ChEMBL
LigandPNGBDBM223080((E)-N'-(1-(3-(4-fluorophenyl)-5-phenyl-4,5-dih...)
Affinity DataIC50: 190nMAssay Description:Inhibition of mouse Ecto-5'-nucleotidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed