BDBM22307 N-methyl indole sulfonamide, 39::N-{2-[2-(1-benzofuran-2-yl)-1-methyl-1H-indol-3-yl]ethyl}-4-pentylbenzene-1-sulfonamide

SMILES CCCCCc1ccc(cc1)S(=O)(=O)NCCc1c(-c2cc3ccccc3o2)n(C)c2ccccc12

InChI Key InChIKey=TZHCRXDVSUNXQA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 22307   

TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Rabbit)
Bristol-Myers Squibb

LigandPNGBDBM22307(N-{2-[2-(1-benzofuran-2-yl)-1-methyl-1H-indol-3-yl...)
Affinity DataIC50: 143nMAssay Description:The inhibitory activity of the compounds against purified 15-LO enzyme was determined using a standard colorimetric assay in which the lipid hydroper...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2008
Entry Details Article
PubMed