BDBM223015 US10034939, Example 17::US10967060, Example 17::US11207302, Example 17::US20240173303, Example 17::US9320732, 17::US9789094, 17

SMILES Cc1cc(NC(=NO)c2nonc2NCCNS(C)(=O)=O)ccc1F

InChI Key InChIKey=UCXWHYTXLXWOJD-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 223015   

TargetIndoleamine 2,3-dioxygenase 1(Human)
Incyte

US Patent
LigandPNGBDBM223015(US9320732, 17 | US10034939, Example 17 | US9789094...)
Affinity DataIC50: 500nMpH: 6.5 T: 2°CAssay Description:Human indoleamine 2,3-dioxygenasae (IDO) with an N-terminal His tag was expressed in E. coli and purified to homogeneity. IDO catalyzes the oxidative...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2017
Entry Details
Go to US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Incyte

US Patent
LigandPNGBDBM223015(US9320732, 17 | US10034939, Example 17 | US9789094...)
Affinity DataIC50: 500nMpH: 6.5 T: 2°CAssay Description:Human indoleamine 2,3-dioxygenasae (IDO) with an N-terminal His tag was expressed in E. coli and purified to homogeneity. IDO catalyzes the oxidative...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2018
Entry Details
Go to US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Incyte

US Patent
LigandPNGBDBM223015(US9320732, 17 | US10034939, Example 17 | US9789094...)
Affinity DataIC50: 500nMpH: 6.5 T: 2°CAssay Description:Human indoleamine 2,3-dioxygenasae (IDO) with an N-terminal His tag was expressed in E. coli and purified to homogeneity. IDO catalyzes the oxidative...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2018
Entry Details
Go to US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Incyte

US Patent
LigandPNGBDBM223015(US9320732, 17 | US10034939, Example 17 | US9789094...)
Affinity DataIC50: 500nMAssay Description:Human indoleamine 2,3-dioxygenasae (IDO) with an N-terminal His tag was expressed in E. coli and purified to homogeneity. IDO catalyzes the oxidative...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
Go to US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Incyte

US Patent
LigandPNGBDBM223015(US9320732, 17 | US10034939, Example 17 | US9789094...)
Affinity DataIC50: 500nMAssay Description:Human indoleamine 2,3-dioxygenasae (IDO) with an N-terminal His tag was expressed in E. coli and purified to homogeneity. IDO catalyzes the oxidative...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2021
Entry Details
Go to US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Incyte

US Patent
LigandPNGBDBM223015(US9320732, 17 | US10034939, Example 17 | US9789094...)
Affinity DataIC50: 500nMAssay Description:Human indoleamine 2,3-dioxygenasae (IDO) with an N-terminal His tag was expressed in E. coli and purified to homogeneity. IDO catalyzes the oxidative...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
Go to US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Incyte

US Patent
LigandPNGBDBM223015(US9320732, 17 | US10034939, Example 17 | US9789094...)
Affinity DataIC50: 500nMAssay Description:Human indoleamine 2,3-dioxygenase (IDO) with an N-terminal His tag was expressed in E. coli and purified to homogeneity. IDO catalyzes the oxidative ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
Go to US Patent