BDBM223001 US10034939, Example 3::US10967060, Example 3::US20240173303, Example 3::US9320732, 3::US9789094, 3

SMILES NS(=O)(=O)NCCCNc1nonc1C(Nc1ccc(F)c(Br)c1)=NO

InChI Key InChIKey=XTVPFVFMVZWJFS-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 223001   

TargetIndoleamine 2,3-dioxygenase 1(Human)
Incyte

US Patent
LigandPNGBDBM223001(US9320732, 3 | US10034939, Example 3 | US9789094, ...)
Affinity DataIC50: 100nMpH: 6.5 T: 2°CAssay Description:Human indoleamine 2,3-dioxygenasae (IDO) with an N-terminal His tag was expressed in E. coli and purified to homogeneity. IDO catalyzes the oxidative...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2017
Entry Details
Go to US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Incyte

US Patent
LigandPNGBDBM223001(US9320732, 3 | US10034939, Example 3 | US9789094, ...)
Affinity DataIC50: 100nMpH: 6.5 T: 2°CAssay Description:Human indoleamine 2,3-dioxygenasae (IDO) with an N-terminal His tag was expressed in E. coli and purified to homogeneity. IDO catalyzes the oxidative...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2018
Entry Details
Go to US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Incyte

US Patent
LigandPNGBDBM223001(US9320732, 3 | US10034939, Example 3 | US9789094, ...)
Affinity DataIC50: 100nMpH: 6.5 T: 2°CAssay Description:Human indoleamine 2,3-dioxygenasae (IDO) with an N-terminal His tag was expressed in E. coli and purified to homogeneity. IDO catalyzes the oxidative...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2018
Entry Details
Go to US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Incyte

US Patent
LigandPNGBDBM223001(US9320732, 3 | US10034939, Example 3 | US9789094, ...)
Affinity DataIC50: 100nMAssay Description:Human indoleamine 2,3-dioxygenasae (IDO) with an N-terminal His tag was expressed in E. coli and purified to homogeneity. IDO catalyzes the oxidative...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
Go to US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Incyte

US Patent
LigandPNGBDBM223001(US9320732, 3 | US10034939, Example 3 | US9789094, ...)
Affinity DataIC50: 100nMAssay Description:Human indoleamine 2,3-dioxygenasae (IDO) with an N-terminal His tag was expressed in E. coli and purified to homogeneity. IDO catalyzes the oxidative...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2021
Entry Details
Go to US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Incyte

US Patent
LigandPNGBDBM223001(US9320732, 3 | US10034939, Example 3 | US9789094, ...)
Affinity DataIC50: 100nMAssay Description:Human indoleamine 2,3-dioxygenase (IDO) with an N-terminal His tag was expressed in E. coli and purified to homogeneity. IDO catalyzes the oxidative ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
Go to US Patent