BDBM222995 US9315519, 18

SMILES CN1CCN(C(=O)C1)c1cccc2[C@H](N(CCc12)C(=O)C1CC2(C1)CCN(CC2)C(N)=N)C(=O)Nc1ccc(cc1)C(O)=O

InChI Key InChIKey=JNKXCIFSFSRCSL-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 222995   

TargetCoagulation factor XI(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM222995(US9315519, 18)
Affinity DataKi: <5nMpH: 7.4Assay Description:Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 145 mM NaCl, 5 mM KCl, and 0.1% PEG 8000 (polyethylene glycol; JT Bake...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2017
Entry Details
Go to US Patent