BDBM222963 US9315514, 11

SMILES CC(C)(C)[C@@]1(C)OCO[C@]23C=C[C@@]4(C[C@H]12)[C@H]1Cc2ccc(O)c5O[C@@H]3[C@]4(CCN1CC1CC1)c25

InChI Key InChIKey=OOAABOYCKWLINM-UHFFFAOYSA-N

Data  1 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 222963   

TargetMu-type opioid receptor(Human)
Rhodes Technologies

US Patent
LigandPNGBDBM222963(US9315514, 11)
Affinity DataEC50:  1.56nMpH: 7.4 T: 2°CAssay Description:[35S]GTPγS functional assays were conducted using freshly thawed μ-receptor membranes prepared in-house from a cell line expressing recombin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2017
Entry Details
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TargetKappa-type opioid receptor(Human)
Rhodes Technologies

US Patent
LigandPNGBDBM222963(US9315514, 11)
Affinity DataEC50:  7.76nMpH: 7.4 T: 2°CAssay Description:Functional [35S]GTPγS binding assays were conducted as follows. κ opioid receptor membrane solution was prepared by sequentially adding f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2017
Entry Details
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TargetKappa-type opioid receptor(Human)
Rhodes Technologies

US Patent
LigandPNGBDBM222963(US9315514, 11)
Affinity DataKi:  0.440nM ΔG°:  -12.8kcal/molepH: 7.4 T: 2°CAssay Description:Radioligand dose displacement assays used 0.4 nM [3H]-U69,593 (GE Healthcare, Piscataway, N.J.; 40 Ci/mmole) with 15 μg membrane protein (recombin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2017
Entry Details
Go to US Patent