BDBM22294 4-({2-[2-(4-methoxyphenyl)-1H-indol-3-yl]ethyl}sulfamoyl)benzoic acid::tryptamine sulfonamide, 37d

SMILES COc1ccc(cc1)-c1[nH]c2ccccc2c1CCNS(=O)(=O)c1ccc(cc1)C(O)=O

InChI Key InChIKey=DBXIYNXFYNFMHA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 22294   

TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Rabbit)
Bristol-Myers Squibb

LigandPNGBDBM22294(4-({2-[2-(4-methoxyphenyl)-1H-indol-3-yl]ethyl}sul...)
Affinity DataIC50: 1.00E+4nMAssay Description:The inhibitory activity of the compounds against purified 15-LO enzyme was determined using a standard colorimetric assay in which the lipid hydroper...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2008
Entry Details Article
PubMed