BDBM222540 US9315489, 76

SMILES FC(F)(Cl)Oc1ccc(NC(=O)c2cnc(Cl)c(c2)-c2cncnc2)cc1

InChI Key InChIKey=BHFPNMRGSVUFLM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 222540   

TargetTyrosine-protein kinase ABL1 [64-515](Human)
Novartis

US Patent
LigandPNGBDBM222540(US9315489, 76)
Affinity DataIC50: 2.90nMpH: 7.5 T: 2°CAssay Description:All assays were performed in 384-well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, as well as four 8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2017
Entry Details
Go to US Patent