BDBM222345 (E)-5-(4-hydroxy-3-((4-methylpiperazin-1-yl)methyl)styryl)-4-(hydroxylmethyl)-2-methylpyridin-3-ol (11f)

SMILES CN1CCN(Cc2cc(\C=C\c3cnc(C)c(O)c3CO)ccc2O)CC1

InChI Key InChIKey=OVNHHTUVVJQXSL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 222345   

TargetAcetylcholinesterase(Electric eel)
Sichuan University

LigandPNGBDBM222345((E)-5-(4-hydroxy-3-((4-methylpiperazin-1-yl)methyl...)
Affinity DataIC50: 2.61E+5nMAssay Description:For AChE or BuChE inhibition assays, a reaction mixture (100 mL) containing acetylthiocholine iodide (1 mmol/L, 30 mL) or butyrylthiocholine iodide (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2017
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Sichuan University

LigandPNGBDBM222345((E)-5-(4-hydroxy-3-((4-methylpiperazin-1-yl)methyl...)
Affinity DataIC50: 2.21E+4nMpH: 7.4Assay Description:Recombinant human MAO-A and MAO-B (5 mg/mL) were purchased from Sigma-Aldrich, pre-aliquoted and stored at -80 °C. Solutions of test compounds we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2017
Entry Details Article
PubMed