BDBM222289 4-(Benzo[d][1,3]dioxol-5-yl)-2-(2-pyrrolidin-1-yl-2-oxoethyl)-6-phenylpyridazin-3(2H)-one (7)

SMILES O=C(Cn1nc(cc(-c2ccc3OCOc3c2)c1=O)-c1ccccc1)N1CCCC1

InChI Key InChIKey=YOZBJOPTDGNGIW-UHFFFAOYSA-N

Data  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 222289   

TargetProstaglandin G/H synthase 2(Human)
Panjab University

LigandPNGBDBM222289(4-(Benzo[d][1,3]dioxol-5-yl)-2-(2-pyrrolidin-1-yl-...)
Affinity DataKd:  51.3nMAssay Description:Inhibitory activity of the synthesized compounds on COX-1 and COX-2 enzymes were evaluated at 40 μm using the COX Inhibitor Screening Assay Kit ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2017
Entry Details Article
PubMed