BDBM222189 6-(Dimethylamino)-3-(3'-hydroxy-4'-methoxyphenyl)-2,3-dihydronaphtho[1,8-de][1,2]thiazine 1,1-dioxide (7k)

SMILES COc1ccc(cc1O)C1NS(=O)(=O)c2cccc3c(ccc1c23)N(C)C

InChI Key InChIKey=NGSBQVKCJPOFSC-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 222189   

TargetAlkaline phosphatase, tissue-nonspecific isozyme(Bovine)
University of Karachi

LigandPNGBDBM222189(6-(Dimethylamino)-3-(3'-hydroxy-4'-methoxy...)
Affinity DataIC50: 270nMpH: 9.8 T: 2°CAssay Description:Alkaline phosphatase (b-TNAP, c-IAP purchased from Calzyme Laboratories, Inc. USA) inhibition assay of different cyclic sulfonamides was performed us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2017
Entry Details Article
PubMed
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Bovine)
University of Karachi

LigandPNGBDBM222189(6-(Dimethylamino)-3-(3'-hydroxy-4'-methoxy...)
Affinity DataIC50: 1.69E+3nMpH: 9.8 T: 2°CAssay Description:Alkaline phosphatase (b-TNAP, c-IAP purchased from Calzyme Laboratories, Inc. USA) inhibition assay of different cyclic sulfonamides was performed us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2017
Entry Details Article
PubMed
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Bovine)
University of Karachi

LigandPNGBDBM222189(6-(Dimethylamino)-3-(3'-hydroxy-4'-methoxy...)
Affinity DataIC50: 270nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetIntestinal-type alkaline phosphatase(Bovine)
Monash University

Curated by ChEMBL
LigandPNGBDBM222189(6-(Dimethylamino)-3-(3'-hydroxy-4'-methoxy...)
Affinity DataIC50: 1.69E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed