BDBM222185 6-(Dimethylamino)-3-(3',5'-dichloro-2-hydroxyphenyl)-2,3-dihydronaphtho[1,8-de][1,2]thiazine 1,1-dioxide (7g)

SMILES CN(C)c1ccc2C(NS(=O)(=O)c3cccc1c23)c1cc(Cl)cc(Cl)c1O

InChI Key InChIKey=UCCHQPAEZRYIGV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 222185   

TargetAlkaline phosphatase, tissue-nonspecific isozyme(Bovine)
University of Karachi

LigandPNGBDBM222185(6-(Dimethylamino)-3-(3',5'-dichloro-2-hydr...)
Affinity DataIC50: 270nMpH: 9.8 T: 2°CAssay Description:Alkaline phosphatase (b-TNAP, c-IAP purchased from Calzyme Laboratories, Inc. USA) inhibition assay of different cyclic sulfonamides was performed us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2017
Entry Details Article
PubMed
TargetIntestinal-type alkaline phosphatase(Bovine)
University of Karachi

LigandPNGBDBM222185(6-(Dimethylamino)-3-(3',5'-dichloro-2-hydr...)
Affinity DataIC50: 380nMpH: 9.8 T: 2°CAssay Description:Alkaline phosphatase (b-TNAP, c-IAP purchased from Calzyme Laboratories, Inc. USA) inhibition assay of different cyclic sulfonamides was performed us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2017
Entry Details Article
PubMed