BDBM222181 6-(Dimethylamino)-3-(4'-methylphenyl)-2,3-dihydronaphtho[1,8-de][1,2]thiazine 1,1-dioxide (7c)

SMILES CN(C)c1ccc2C(NS(=O)(=O)c3cccc1c23)c1ccc(C)cc1

InChI Key InChIKey=HQHMFXZCQFFWKO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 222181   

TargetAlkaline phosphatase, tissue-nonspecific isozyme(Bovine)
University of Karachi

LigandPNGBDBM222181(6-(Dimethylamino)-3-(4'-methylphenyl)-2,3-dihy...)
Affinity DataIC50: 460nMpH: 9.8 T: 2°CAssay Description:Alkaline phosphatase (b-TNAP, c-IAP purchased from Calzyme Laboratories, Inc. USA) inhibition assay of different cyclic sulfonamides was performed us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2017
Entry Details Article
PubMed
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Bovine)
University of Karachi

LigandPNGBDBM222181(6-(Dimethylamino)-3-(4'-methylphenyl)-2,3-dihy...)
Affinity DataIC50: 460nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed