BDBM222156 6,8-dibromo-2,2-dimethyl-2,3-dihydroquinazolin-4(1H)-one (5a)

SMILES CC1(C)NC(=O)c2cc(Br)cc(Br)c2N1

InChI Key InChIKey=GHVVJQSMCRYHRG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 222156   

TargetAcetylcholinesterase(Electric eel)
University of Sargodha

LigandPNGBDBM222156(6,8-dibromo-2,2-dimethyl-2,3-dihydroquinazolin-4(1...)
Affinity DataIC50: 2.50E+4nMpH: 8.0Assay Description:Galantamine was used as reference drugs. The synthesized quinazolines were dissolved in 0.1 M phosphate buffer of pH 8.0. (KH2PO4/K2HPO4. The reactio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2017
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Horse)
University of Sargodha

LigandPNGBDBM222156(6,8-dibromo-2,2-dimethyl-2,3-dihydroquinazolin-4(1...)
Affinity DataIC50: 8.62E+4nMpH: 8.0Assay Description:Galantamine was used as reference drugs. The synthesized quinazolines were dissolved in 0.1 M phosphate buffer of pH 8.0. (KH2PO4/K2HPO4. The reactio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2017
Entry Details Article
PubMed